How to diagnose recurrent abortion
● ● colt is already late childbearing, and 30 at the age of first pregnancy, do not know why, just 2 months time to a miscarriage. Because at that time did not know was pregnant, self-care that there is no serious reason. Can be passed a year later, which led to the same situation. At this time he was consulted by the doctor reasons, some doctors say it can not yet determine whether recurrent early spontaneous abortion, because in line with such a diagnosis must be three times or more than 3 times. With this argument, pony and their families to pay attention to how to improve prenatal care. Available at the third pregnancy, the same as with the previous two outcomes occurred. In doing so they are very sad, this continues to be done? They decided to look for infertility expert advice, decided to check out the real cause of abortion to make a clear diagnosis, in order to prevent such a tragedy from happening again.
● ● recurrent early spontaneous abortion (ERSA) to diagnose the problem, has always had academic controversy. Due to the constraints of the traditional concept of the past consecutive three times or more than 3 times before called ERSA, some scholars believe that only happened three times a row before abortions can be related to the necessary checks to establish, for the disease. In fact, compare the current medical development, and relatively complete examinations of the case should not be insisted and so there is no need to check three times before, at present more scholars tend to row 2 should be checked on the idea of abortion. In particular, older maternal age (over 35 years of age), but also early examination, early diagnosis, as soon as possible to take measures.
● ● With regard to ERSA diagnosis, at present there are two major ways, one is diagnosed before pregnancy, one is diagnosed after pregnancy. These two diagnostics is also very important.
● ● diagnosed before pregnancy, the method and content of
If you have already taken place in unexplained abortions, especially those who have already taken place twice again before the pregnancy, the pregnancy should be careful to do the relevant checks to avoid the recurrence of tragedy, to pregnant women cause more physical and psychological harm.
● ● initiative to introduce themselves in general. Go to the hospital at the time of inspection, the doctor should explain the actual situation of their own, such as menstrual conditions, family circumstances, the disease situation in the past, is not smoking, alcohol consumption, whether contact with hazardous substances, radiation, etc., should make it clear that analysis for the doctor to provide information on disease. To the hospital, the patients also need to determine the height, weight, blood pressure, associated gynecological and medical examinations to see if there uterus, attachment, infection, developmental abnormalities, etc., these checks are very simple check, it can at a glance.
● ● The check can only be a general examination to detect some complex diseases, but also rely on lab examination. The inspection is the most common genetic examination. Check includes pedigree analysis, karyotype analysis, molecular genetic diagnosis. If you have any questions about uterine tube, but also for hysterosalpingography, ultrasound, laparoscopy and hysteroscopy, if necessary, they would even be magnetic resonance imaging examination. The purpose of these inspections is to understand the development of reproductive organs, find, and ERSA-related causes.
● ● endocrine examination is also an important component of inspection and has a very important clinical significance, should actively cooperate with the doctor. Basal body temperature is to check there is no normal ovulation, luteal function is not normal for an important reference index can be measured at home themselves, will tell the doctor can determine the result. Pairs of suspected endometrial possible cause abortion, but also for endometrial biopsy, which is often said that the diagnostic curettage (curettage), so analysis of endometrium, luteal phase and others are not normal. Endocrine inspection also includes examination of serum hormones. Serum progesterone measurement can be combined with curettage is not further defined luteal function has been an obstacle; serum prolactin determination to understand the luteal phase is not subject to outside influence. Although the anterior pituitary prolactin secretion, but the maintenance of luteal prolactin plays a decisive role, too low, too high can lead to luteal insufficiency. Must be explained that, check serum prolactin should be 8-9 points collected in the morning, preferably every 15 minutes continuously three times a mixture of blood sent for testing, because the hormone secreted at night and the morning of high secretory low, to prevent misdiagnosis; determination of thyroid function is also necessary, the main check thyroid-stimulating hormone, when the abnormal again when checking three triiodothyronine, thyroxine, if these checks there is no problem, you should check the anti-thyroid antibodies.
● ● exclude infection factors. Infection is one important factor triggered ERSA, especially in premature rupture of membranes, preterm delivery, etc., often have a certain relationship with the infection. Some infections, pregnant women do not necessarily obvious symptoms, so those who have a history of abortion, should be carried out relevant examinations. Common check Chlamydia trachomatis, Ureaplasma urealyticum, Mycoplasma hominis, Mycoplasma genitalium, β-hemolytic streptococcus and other training, TORCH testing (toxoplasmosis, rubella virus, cytomegalovirus, herpes virus), so as to understand the reproductive system is not to be infected.
After pregnancy diagnosis methods and content of
● ● Some patients have been pregnant, but fears of ERSA problem, is not it also be monitoring, notice it? The answer is yes. The current inspection methods are more, mainly through the tracking and monitoring during pregnancy, hormone determination, ultrasound examination, genetic screening to determine the underlying causes of ERSA occurred.
● ● pregnancy monitoring is very important. Any pregnant women, abortion occurred, once again, pregnant, should be tracking and monitoring, if unusual, should promptly take appropriate measures to avoid tragedy.
● ● hormone human chorionic gonadotropin measurement is mainly β (β-HCG) measurement, magnetic, progesterone determination. Determination of β-HCG can understand luteal function in pregnant women, if we find β-HCG is low, it indicates that pregnancy luteal phase defect, progesterone hormone deficiency are prone to miscarriage. For the estrogen and progesterone determination, but also can be used as a diagnostic reference, it is reported prone to an early abortion increase slowly.
● ● ultrasound. This is a simple way to check, as long as the operating properly, will not adversely affect the fetus, is very commonly used in clinical screening method. B-can observe the fetal heart rate fluctuations, pregnancy sac size, embryo implantation, etc., you can judge such information embryo, the fetus’s safety.
● ● immunological diagnosis. The system checks, is a very clinical significance of diagnostic methods. Did not find any reason, on many occasions there is no other abnormal signs of abortion, age over 35 years, the embryo has a normal karyotype abortion occurs, can be carried out immunological tests. Determination of anti-sperm antibodies, human leukocyte antigen examination, maternal anti-paternal lymphocyte cytotoxicity antibody, blood group and anti-blood group antibody, anti-nuclear antibodies and anti-thyroid antibody, natural killer cell activity assay, cotton-padded clothes and complement C3 complex determination Determination of anti-phospholipid antibodies, are commonly used inspection methods can be determined in accordance with the general ERSA test items.
● ● detection is very important, by determining the causes can be targeted to prevent, can effectively reduce or prevent abortion from happening again. Of course, these tests are more cumbersome and require a certain costs, but in order to properly nurture their children, in order to avoid a tragedy, we should actively carry out the necessary checks.