Custom abortion and anti-cardiolipin antibodies

Anticardiolipin antibodies are not limited to gynecology, the diagnosis of other diseases, it is often done anticardiolipin antibodies.

 Reference value of ACA-IgG-BI <1.42 ACA-IgA-BI <1.42 Note: BI-binding index

 Anticardiolipin antibodies (ACA) detected ACA class for a group of circulating autoantibodies IgG.IgM.IgA, in which a high level of IgG based on primary diagnosis of antiphospholipid syndrome is most specific; ACA in SLE, the positive rate of 20 % -50%, mainly IgG and IgM type, thrombosis, habits mainly with abortion and thrombocytopenia IgG type of antibody, while the IgM type and hemolytic anemia and neutropenia-related; Sjögren’s syndrome in the IgG type of the high rate of appearance of antibodies, IgA-type antibody and habitual abortion, and severe Guillain – Barre syndrome.

 The higher the level of ACA, the more prone to complications. In addition, in other rheumatic diseases, drugs, lupus, cancer and infection can occur in the ACA, but few occurrence of the above complications, the reasons for the existence of such differences may be related to the type of antibody, the level of affinity, specificity and integration environment, genetic factors have a certain relationship.

 Such as the ACA-positive patients, then the high incidence of habitual abortion may be duplication of abortion, embryo death, perinatal fetal viability or fetal development, Low and poor. However, with the ACA is not the only abortion-related antibodies, and should be integrated with other indicators to consider.