Causes of maternal easy abortion

A healthy combination of egg and sperm, the normal uterus and fallopian tubes, the appropriate biochemical environment and endocrine balance, all the conditions of pregnancy and maintenance of pregnancy, in which any of these factors may lead to abnormal miscarriage.

 Abortion is not only caused physical harm to patients would also bring psychological blow to the family. Abortion occurred 3 consecutive times or more, medicine is called habitual abortion. Habitual abortion merely a symptom, but in this performance behind the hidden causes of the disease, the most common cause of the following:

 Genetic factors: family marriage, the couple either one or both chromosomal abnormalities, both husband and wife closer blood ties, the more easily the next generation of chromosomal abnormalities manifested as dominant, chromosomal abnormalities of embryos can not survive more than a result of abortion, while others appeared teratogenic, fetal development retardation, or, having survived, but manifested as chromosomal abnormalities dominant inheritance.

 Uterine abnormalities: Congenital uterine malformations such as double uterine horn, saddle-shaped uterus, the uterus is too small, intrauterine adhesions, uterine fibroids, also may cause habitual abortion. Uterus is Yunluan implantation, development and growth of the premises is the embryonic development of soil, the uterus is not an exception to the normal development of Yunluan will cause miscarriage and should therefore be actively treated. Uterine hypoplasia, the uterus is too small can be used estrogen therapy, commonly used DES 0.5mg ~ 1mg, daily one time, bedtime oral, from the 5th day of menstrual cycle, used in conjunction on the 20th, a total of 3 to 4 cycles; can also be used to stimulate foreign body law, such as placing a small IUD within the uterus, prompting the uterus increases; sometimes be necessary for surgical, such as the removal of intrauterine adhesions, uterine plastic surgery, myomectomy and so on.

 Luteal phase defect: ovarian rupture after ovulation, luteal formation, luteal secretion of progesterone and estrogen. Conception, the corpus luteum to maintain pregnancy, 4 to 6 months to start degradation, early pregnancy corpus luteum life span and its function is affected by human chorionic gonadotropin (HCG) role. Yunluan after implantation in the womb, from eggs to embryonic cells differentiated syncytiotrophoblast layer, in contact with the uterine decidua in the future develop into the placenta, syncytiotrophoblast secretion of HCG will soon enter the matrix, so that luteal life expectancy, and to stimulate its synthesis of progesterone to maintain pregnancy.

 Maternal-fetal blood group incompatibility: The most common for the ABO blood group incompatibility, you rarely get a RH-based, MN system blood group incompatibility. If the mother and fetal blood group incompatibility between the fetal antigens from the father’s side has entered the mother’s body to produce antibodies through the placenta into the fetal blood circulation, acting on the red blood cells, so that destruction of hemolysis, severe fetal death can, resulting in late abortion. In the ABO blood group incompatibility, the majority of pregnant women for the O-type blood, the husband of A, B or type AB blood type, if the fetal blood is type A or B type, is likely to occur late abortion, but the incidence of such cases is not high.

 Cervical relaxation within the mouth: habitual late abortion often caused by the relaxation of the cervix within the mouth. Damage due to surgery, a few are congenital abnormalities caused by population expansion of the cervix, and uterus isthmus defects in the mid-pregnancy, amniotic fluid increased, the fetus grew up in increased intrauterine pressure, fetal sac inside the mouth from the cervical prominent progressive cervical canal shortened, expansion, when the pressure increased to a certain extent, a sudden rupture of membranes, resulting in fetal abortion discharged. Such repeated abortion, abortion occurred in accordance with the previous period, select 12 to 20 weeks of pregnancy uterine ligation within the mouth and after I tocolysis therapy, to full-term pregnancy has threatened labor or cesarean section again when the program has been implemented removal of stitches.

 Habitual abortion more complicated reasons, and only find out the reasons, targeted therapy to achieve satisfactory results with this disease, women should go to hospital for a comprehensive and systematic examination. After an abortion, especially ovarian and uterine dysfunction, hypoplasia of the women, preferably after three normal menstrual cycle after pregnancy, in order to have sufficient time to restore the body hormones and endometrial function.

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